Yoshihiro Maruo Selected Research

Crigler-Najjar Syndrome

2/2016	Genotype of UGT1A1 and phenotype correlation between Crigler-Najjar syndrome type II and Gilbert syndrome.
11/2004	Two linked polymorphic mutations (A(TA)7TAA and T-3279G) of UGT1A1 as the principal cause of Gilbert syndrome.
9/2004	Genetic polymorphisms of bilirubin uridine diphosphate-glucuronosyltransferase gene in Japanese patients with Crigler-Najjar syndrome or Gilbert's syndrome as well as in healthy Japanese subjects.
11/2003	A novel missense mutation of the bilirubin UDP-glucuronosyltransferase gene in a Turkish patient with Crigler-Najjar syndrome type 1.
1/2002	[UDP-glucuronosyltransferase].

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Yoshihiro Maruo Research Topics

Disease

7	Gilbert Disease 02/2016 - 01/2002
6	Hyperbilirubinemia 11/2017 - 09/2004
5	Crigler-Najjar Syndrome 02/2016 - 01/2002
4	Neoplasms (Cancer) 01/2019 - 08/2004
3	Retinopathy of Prematurity (Retrolental Fibroplasia) 01/2021 - 01/2019
3	Kernicterus 01/2021 - 12/2015
3	Jaundice (Icterus) 07/2014 - 03/2011
2	Ganglion Cysts (Ganglion) 08/2022 - 11/2020
2	Seizures (Absence Seizure) 06/2021 - 04/2010
2	Drug Resistant Epilepsy 06/2021 - 06/2016
2	Body Weight (Weight, Body) 01/2021 - 11/2011
2	Type 2 Diabetes Mellitus (MODY) 11/2019 - 02/2012
2	Primary Immunodeficiency Diseases 01/2019 - 12/2016
2	Congenital Hypothyroidism (Cretinism) 04/2016 - 11/2008
2	Hypothyroidism 04/2016 - 11/2008
2	type 2 Crigler Najjar syndrome 02/2016 - 03/2011
2	Drug-Related Side Effects and Adverse Reactions 12/2011 - 04/2005
2	Carcinogenesis 12/2011 - 04/2005
2	Hemolysis 03/2011 - 02/2009
2	Hereditary Spherocytosis 03/2011 - 02/2009
1	Lysinuric Protein Intolerance 10/2022
1	Hypoglycemia (Reactive Hypoglycemia) 06/2021
1	Multiple Organ Failure (MODS) 06/2021
1	Glucose Intolerance 06/2021
1	Respiratory Distress Syndrome (Acute Respiratory Distress Syndrome) 06/2021
1	Acute Necrotizing Pancreatitis 06/2021
1	MEHMO syndrome 06/2021
1	Pancreatitis 06/2021
1	Obesity 06/2021
1	Weight Gain 01/2021
1	Brain Diseases (Brain Disorder) 01/2021
1	Hereditary Hyperbilirubinemia (Rotor Syndrome) 01/2021
1	Lung Diseases (Lung Disease) 01/2020
1	Cognitive Dysfunction 01/2020
1	Iron Deficiencies 01/2020
1	Interstitial Lung Diseases (Interstitial Lung Disease) 01/2020
1	Experimental Arthritis 01/2020
1	Birth Injuries (Birth Injury) 11/2019
1	Birth Weight (Birth Weights) 11/2019
1	Mason-Type Diabetes 11/2019
1	Type 2 Maturity-Onset Diabetes of the Young 11/2019
1	Hyperplasia 01/2019
1	Herpesviridae Infections (Herpesvirus Infection) 01/2019
1	Respiratory Tract Infections (Respiratory Tract Infection) 01/2019
1	Hemorrhage 05/2018
1	Bradycardia 01/2018
1	Hypotension (Low Blood Pressure) 01/2018
1	Mucocutaneous Lymph Node Syndrome (Kawasaki Disease) 11/2016
1	Myocarditis (Carditis) 11/2016
1	Shock 11/2016
1	Disseminated Intravascular Coagulation 11/2016
1	Renal Insufficiency (Renal Failure) 11/2016
1	Neuroepithelial Neoplasms (Gliomatosis Cerebri) 06/2016
1	Thyrotoxicosis 01/2016
1	Intellectual Disability (Idiocy) 01/2016
1	Sleep Initiation and Maintenance Disorders (Insomnia) 01/2016
1	Leukemia 01/2016
1	Liver Diseases (Liver Disease) 01/2016

Drug/Important Bio-Agent (IBA)

14	BilirubinIBA 01/2021 - 01/2002
7	Glucuronosyltransferase (UDP Glucuronosyltransferase)IBA 11/2017 - 09/2004
5	bilirubin glucuronoside glucuronosyltransferaseIBA 07/2014 - 11/2003
4	Uridine Diphosphate (UDP)IBA 11/2017 - 09/2004
3	Insulin (Novolin)FDA Link 06/2021 - 02/2012
2	Proteins (Proteins, Gene)FDA Link 01/2021 - 01/2021
2	Bevacizumab (Avastin)FDA Link 01/2021 - 01/2019
2	Histamine (Histamine Dihydrochloride)FDA Link 11/2020 - 04/2010
2	SteroidsIBA 11/2016 - 09/2011
2	Intravenous Immunoglobulins (IVIG)FDA Link 11/2016 - 11/2011
2	Dual OxidasesIBA 04/2016 - 11/2008
2	UGT1A1 enzymeIBA 11/2015 - 03/2011
2	DNA (Deoxyribonucleic Acid)IBA 07/2006 - 01/2003
1	Amino Acids FDA Link 10/2022
1	Nicotine FDA Link 08/2022
1	Nicotinic Receptors (Nicotinic Acetylcholine Receptor)IBA 08/2022
1	Glucose (Dextrose)FDA LinkGeneric 06/2021
1	Mydriatics (Cycloplegics)IBA 01/2021
1	CationsIBA 11/2020
1	AntibodiesIBA 01/2020
1	Fibrinogen (Factor I)FDA Link 01/2020
1	Collagen Type II (Type II Collagen)IBA 01/2020
1	GlucokinaseIBA 11/2019
1	Phosphatidylinositol 3-Kinases (PI 3 Kinase)IBA 01/2019
1	HemosiderinIBA 05/2018
1	Verapamil (Calan)FDA LinkGeneric 01/2018
1	Phosphatidylinositol 3-Kinase (1 Phosphatidylinositol 3 Kinase)IBA 12/2016
1	2,6-dinitrotoluene (DNT)IBA 06/2016
1	Thyroglobulin FDA Link 04/2016
1	UridineIBA 02/2016
1	Triiodothyronine (Liothyronine)FDA LinkGeneric 01/2016
1	Thyroxine (Levothyroxine)FDA LinkGeneric 01/2016

Therapy/Procedure

4	Therapeutics 06/2021 - 01/2016
2	Drug Therapy (Chemotherapy) 01/2016 - 09/2011
2	Liver Transplantation 12/2015 - 07/2006
1	Critical Care (Surgical Intensive Care) 06/2021
1	Ketogenic Diet 06/2021
1	Hematopoietic Stem Cell Transplantation 01/2019
1	Intraocular Injections 01/2019
1	Intravitreal Injections 01/2019
1	Aftercare (After-Treatment) 11/2016
1	Withholding Treatment 01/2016